Drinking coffee on an empty stomach is an unhealthy habit that can lead to various health risks, like a damaged stomach lining and increased anxiety. Luckily, you can prevent these potential risks by making sure to eat breakfast before enjoying your morning cuppa. That being said, it's important not to drink coffee excessively throughout the day, and avoid drinking it past 3 p.m. so that you don't interrupt your sleeping schedule.
While they say that the results support moderate coffee drinking as a relatively healthy habit, both Poole and Guallar say the findings don’t go far enough to prompt anyone to change their coffee-drinking habits in the hopes of improving their health. The study did not confirm, for example, that people who do not currently drink coffee should start adding a cup or two a day in order to lower their risk of getting heart disease or any of the other chronic conditions studied. The data also do not support the idea that current coffee drinkers should drink even more coffee to enhance whatever benefits they might be receiving. Too much coffee, the data suggest, starts to bend the benefit curve back down.
In the Hungry For Change Book we discuss the addictive nature of caffeine and when consumed in large quantities, can lead to adrenal fatigue. Coffee is also a diuretic, meaning it purges water from your body. That said, if you want to function at a high level and remain well hydrated, then it would be a better choice to replace coffee with a natural alternative. The list below provides some great tasting substitutes.
Here's what you should know: Collagen is the protein-rich connective material between tissue and bones (so, yup, veg-heads, you’ll have to sit this one out). It comes in a powder form, so you can stir it into pretty much anything to get a major protein boost that will help you kick-start your day. There’s also some preliminary evidence it can help keep your skin hydrated, improve alcohol-induced liver damage, and support joint health. Look for a brand that doesn't change the flavor, like Further Food Collagen Peptides, so you aren't scrunching up your nose at every sip.
The study builds on earlier work in which the two scientists showed caffeine ramps up the functional capacity of the cells that line blood vessels. The drug does so by getting into cells and stoking the mitochondria, structures within the cells that burn oxygen as they turn glucose into energy.“Mitochondria are the powerhouses of the cells,” Haendeler says. One of the things they run on is a protein known as p27. As Haendeler and Altschmied discovered (and describe in the current paper), caffeine works its magic in the major types of heart cells by increasing the amount of p27 in their mitochondria.  
Studies on coffee consumption patterns of both genders indicate that regular coffee drinking lowers the danger of developing gout. Another separate study analysed the health behaviours of almost 90,000 female nurses across 26 years. Far from what most of them expected, a positive correlation between decreased threat for gout and long-term coffee consumption was noted.
For this part of the experiment, 22-month-old mice received caffeine—the daily equivalent of four to five cups of coffee in humans—in their drinking water for 10 days. That was sufficient to raise their mitochondrial respiration to the levels observed in six-month-old mice, according to the study. Analysis showed the old mice had roughly double the amount of p27 in their mitochondria after the 10 days of caffeine.
Alzheimer’s Disease (AD) is a type of disease that causes problems with your memory, thinking and behavior. Symptoms usually develop slowly and get worse over time, becoming severe enough to eventually interfere with daily tasks. If you’ve ever know somebody with AD or dementia, you know how devastating this condition can be, not just on the sufferer but to those around them as well.
You don’t have to be a trained cardiologist to see that that coffee supports heart health. This, it does so by protecting the heart’s muscular chamber against artery damage that may result from inflammation. This way, various heart diseases are warded off including common ailments such as hypertension, thrombosis, heart attack, heart failure, among others
“It has not really been shown that coffee drinking leads to an increase in antioxidants in the body,” Lane tells WebMD. “We know that there are antioxidants in large quantities in coffee itself, especially when it’s freshly brewed, but we don’t know whether those antioxidants appear in the bloodstream and in the body when the person drinks it. Those studies have not been done.”

"Caffeine for treatment of Parkinson disease" Ronald B. Postuma, MD, MSc, Anthony E. Lang, MD, Renato P. Munhoz, MD, Katia Charland, PhD, Amelie Pelletier, PhD, Mariana Moscovich, MD, Luciane Filla, MD, Debora Zanatta, RPh, Silvia Rios Romenets, MD, Robert Altman, MD, Rosa Chuang, MD and Binit Shah, MD. doi:10.1212/WNL.0b013e318263570d August 1, 2012. Abstract. Accessed 15 December 2013.

You might think that since we boil water to brew coffee, you don’t have to worry whether it’s filtered. But Swinney says filtered water is a smart choice, if not for taste, but for health. “Filtered water ensures there are not any unwanted heavy metals like lead or copper, that might be found in old pipes. Tap water also contain many chlorine disinfection byproducts which can be harmful long term,” she says. “You should also avoid using well water unless it’s been tested for contaminants.”
Studies show that coffee boasts of more antioxidant activity compared to the two antioxidant superstars; cocoa, and tea. In fact, a wide range of detailed lab analysis carried out over the years has identified over 1,000 antioxidants in coffee beans – unprocessed at that. Interestingly, hundreds of more antioxidants come up on roasting the beans. What’s more, a 2012 research labeled coffee as one of the core dietary antioxidants source readily available today.

If you can’t go completely black with your coffee, try adding a small amount of stevia. While not 100% perfect, this choice is certainly better than consuming the artificial sweeteners and refined sugar which are usually found in most cups. Coconut sugar or organic maple syrup can also be used, but the real key here is adding a very small amount. Don’t go overboard!
Men who drink coffee may be at a lower risk of developing aggressive prostate cancer. In addition, new research from the Harvard School of Public Health suggests that drinking four or more cups of coffee daily decreased the risk of endometrial cancer in women by 25 percent as compared to women who drank less than one cup a day. Researchers have also found ties between regular coffee drinking and lower rates of liver, colon, breast, and rectal cancers.
If you can’t go completely black with your coffee, try adding a small amount of stevia. While not 100% perfect, this choice is certainly better than consuming the artificial sweeteners and refined sugar which are usually found in most cups. Coconut sugar or organic maple syrup can also be used, but the real key here is adding a very small amount. Don’t go overboard!
There’s no need to try anything crazy; the only performance enhancer you really need is coffee. Research has shown its ability to give workouts a boost and increase athletic performance, and that’s exactly why you’ll find so many Olympians drinking it: One report from the journal Applied Physiology, Nutrition, and Metabolism found the majority of the 20,686 Olympic athletes analyzed had caffeine in their urine.
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