When a group of volunteers received a dose of 100 milligrams (mg) of caffeine, about as much contained in a single cup of coffee, Austrian researchers found a surge in the volunteers’ brain activity, measured by functional magnetic resonance imagery (fMRI), as they performed a memory task. The researchers noted that the memory skills and reaction times of the caffeinated volunteers were also improved when compared to the control group who received a placebo and showed no increase in brain activity.
If you’re working 80 hours a week, getting three hours of sleep a night, and have no energy because you’re living on carb-heavy takeout, drinking coffee non-stop during the day is a problem. It’s not the coffee; it’s the fact that you’re using the coffee as a crutch. Craving a steaming hot cup or two is fine, being totally dependent on coffee to function isn’t.
Other studies have tried to pinpoint exactly what in caffeine is helping to halt the onset of these diseases. A 2014 study (14) found that caffeine blocks various tau receptors (a protein that contributes to brain cell degeneration). Another study found that caffeinated coffee increased GCSF (15) - a substance greatly decreased in Alzheimer’s patients - levels in the bloodstream.